AOD-9604 Peptide for Laboratory Research

AOD-9604 is a synthetic 16-residue peptide described as the N-tyrosyl analogue of the C-terminal region 177–191 of human growth hormone. Its reference sequence is YLRIVQCRSVEGSCGF. The N-terminal tyrosine is a synthetic addition, and the reference structure contains a disulphide bridge between the two cysteine residues. These features describe the literature identity; they do not authenticate a supplied batch.

Formula, mass and registry identifiers above belong to the AOD-9604 record itself and are never inherited from the related fragment; the two differ at their first residue and therefore carry different formulae, masses and CAS records. Sequence identity, disulphide connectivity, content and chromatographic purity are separate analytical questions. A method-specific HPLC result can describe only the tested sample and batch; it is not a universal purity statement for AOD-9604.

Identity and model sources: Heffernan et al. 2001 · PMID 11713213 · Heffernan et al. 2001 · PMID 11673763

Structural ancestry does not establish the signalling profile of intact hGH. The cited work therefore treats receptor behaviour, cellular response and whole-animal measurements as separate research levels. Each result remains conditional on its assay, comparator, species, timing and endpoint.

Heffernan and colleagues used obese mice and β3-adrenergic-receptor knockout mice to examine pathway-related variables, including receptor RNA expression and differences between acute and chronic experimental conditions. Ng and colleagues examined a synthetic hGH terminal domain in obese Zucker rats. These designs can test relationships inside named models, but they neither certify a commercial material nor establish equivalence with full-length hGH.

Mechanism sources: Heffernan et al. 2001 · PMID 11713213 · Ng et al. 2000 · PMID 11146367 · Heffernan et al. 2001 · PMID 11673763

This section describes findings in controlled research and makes no statement about use. The evidence consists of in vitro components, animal models and one secondary review. It does not constitute human intervention evidence, and no publication listed here analyses a Reborn Peptides batch.

Evidence map: PMID 11146367 · PMID 11713213 · PMID 11673763 · PMID 23092275

AOD-9604 and unmodified hGH Fragment 176-191 are two different substances. AOD-9604 has the 16-residue sequence YLRIVQCRSVEGSCGF, beginning with synthetic N-terminal tyrosine (Y). The native fragment has the sequence FLRIVQCRSVEGSCGF, beginning with phenylalanine (F) at hGH residue 176. The difference is exactly at the first residue: synthetic tyrosine versus native phenylalanine.

This one-residue distinction has direct analytical and procurement consequences. The label, product code, batch code, specification, analytical method and COA must all point to the same material. Sequence-derived identifiers and batch documents for the two substances must never be exchanged. In particular, molecular formula, molecular mass and CAS data must not be inherited in either direction.

The shortened form “aod peptide” refers here only to AOD-9604, not to a peptide class. Shared ancestry at the hGH C-terminus does not make the substances synonyms and does not permit experimental findings or analytical records to cross between them. The separate record for HGH Fragment 176-191 preserves that distinction.

Delimitation sources: Heffernan et al. 2001 · PMID 11713213 · Heffernan et al. 2001 · PMID 11673763

No fill quantity, salt form or storage condition is asserted here. Each must be reconciled against the released label, specification and documentation for the applicable batch. Third-party listings place 2 mg and 5 mg presentations alongside one another, but an amount read from one such listing describes that listing alone and cannot document another supplied material.

Laboratories intending to buy aod 9604 should require a traceable chain connecting product designation, product code, label, batch code, specification, analytical method, test date, result and COA. Any inconsistency should be resolved before material is assigned to a controlled study. A numerical HPLC purity result is method- and batch-specific; chromatography alone does not establish the complete sequence or disulphide connectivity.

Published studies address research materials and experimental models, while released analytical documents address a named sample. Neither document type substitutes for the other. Identity statements and any purity value therefore require evidence tied to the same batch.

Analytical context source: Heffernan et al. 2001 · PMID 11673763

AOD-9604 is presented as research material for controlled laboratory work. The literature record is limited to the named assays, animal models, comparators and endpoints. It does not establish a human outcome, certify supplied material or replace batch-specific analytical review.

Research use only. For laboratory research only. Not for human or veterinary use. Not intended to diagnose, treat, cure or prevent any disease. Not a medicinal product, food or cosmetic.